CBD may help increase serotonin levels in your brain, providing relief for anxiety symptoms. Furthermore, CBD can also reduce agitation and insomnia. Furthermore, it may improve mood while relieving pain.
CBD acts to weakly inhibit CYP1A2, potentially increasing exposure to caffeine, theophylline and tizanidine. Furthermore, CBD can interfere with drugs that require this enzyme for metabolism (valproate or clobazam for instance) which are also metabolized by these enzymes; make sure liver enzyme levels are checked prior to and during any treatment plan.
Depression
Though current antidepressant medications are effective in treating anxiety and depression, they often produce unwanted side effects which impair quality of life for their users. Furthermore, some individuals become resistant to them over time.
CBD has demonstrated anxiolytic, antidepressant and antipsychotic properties in animal models. Furthermore, it has demonstrated neuroprotective benefits. Toxicity testing revealed no significant potential drug abuse potential using measures such as the conditioned place preference test, spontaneous withdrawal test or oral self-administration tests used to measure reinforcing properties.
CBD (cannabidiol) is a non-psychoactive compound that works by binding to serotonin receptors to improve mood. Studies have demonstrated its efficacy for relieving anxiety, increasing appetite and soothing sleep disturbances; and aiding depression by raising serotonin levels – however more research must be conducted to confirm these claims. CBD may interact with certain drugs; therefore it’s essential that before starting any CBD treatments it be checked against existing medication labels – for instance it weakly inhibits CYP1A2, increasing exposure to caffeine, theophylline and tizanidine among others.
PTSD
PTSD is a long-term disorder associated with experiencing or witnessing traumatic events. PTSD symptoms may include anxiety, hyper-arousal and persistent memories of trauma; additional signs could include sleep disruption (nightmares or insomnia), daytime fatigue and feelings of detachment from others.
CBD is one of the more than 60 active cannabinoids found in cannabis that has been demonstrated to ease symptoms associated with posttraumatic stress disorder (PTSD). Although further study is warranted, a recent UCL study suggested that prescription marijuana may provide relief for PTSD symptoms.
The Endocannabinoid System (ECS) is an emotional regulation mechanism essential to internal balance. Studies suggest its signalling may be impaired in those living with posttraumatic stress disorder due to an imbalance of CB1 and CB2 receptors; CBD binds with these receptors and reduces inflammation response, helping alleviate anxiety and fear.
At intake appointments, patients provided informed consent, with PCL-5 questionnaires completed every four weeks to assess progress of care. Based on both patient and practitioner preference, CBD could either be added or dropped from care plans.
ALS
CBD (cannabidiol) found in cannabis plants has recently attracted widespread interest as an all-natural way of alleviating symptoms associated with ALS and improving mitochondrial function. More research is necessary in order to fully comprehend how this compound works and if it could indeed help people living with this disease.
Current treatments for ALS spasticity include baclofen and tizanidine, but these have limits in terms of efficacy and tolerability. To overcome these constraints, a new therapy that provides neuroprotective properties along with antispasticity properties would be advantageous.
CBD can be an effective and safe treatment option for neuropathic pain; however, it should only be administered under the guidance of an experienced physician. Before beginning CBD therapy it is crucial to identify risk factors and assess any contraindications. An interprofessional team approach is required in order to maximize outcomes for patients receiving this therapy.
Arthritis
CBD is an important cannabinoid that works to alleviate body pain. Additionally, its anti-inflammatory properties help ease joint stiffness. CBD can be consumed via tinctures, capsules or cannabis oils; topical treatments also may use CBD. Some individuals also turn to it in an effort to combat the effects of rheumatoid arthritis – where immune system cells attack healthy joint cells – by suppressing lymphocyte growth and inhibiting tumor necrosis factor release.
Recent research examined the analgesic effectiveness of plant-derived CBD versus placebo on patients suffering from hand osteoarthritis or psoriatic arthritis. Participants took 20 to 30 mg of synthetic CBD or placebo daily for 12 weeks; no significant change was noted between groups; CBD seemed to act via the endocannabinoid system by binding to ECS receptors and blocking pain signals from reaching the brain, and blocking proinflammatory cytokines like TNF-a and IL1-a which contribute to inflammation.
