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CBD reduces anxiety across multiple animal models, such as the elevated plus maze (EPM) and Vogel conflict test (VCT), with effects dependent on CB1R activation and hippocampal AEA activation. Furthermore, CBD inhibits anticipatory anxiety during contextual fear conditioning paradigms while simultaneously improving extinction training.Contrary to THC and direct CB1R agonists, CBD does not exhibit anxiety-inducing properties at higher dosage levels, suggesting unique mechanisms of action.AnxietyCBD, or cannabidiol (CBD), is a phytocannabinoid found in Cannabis sativa that lacks the psychoactive effects associated with 9-tetrahydrocannabinol (THC). Preclinical studies have demonstrated anxiolytic properties in animal models. CBD modulates multiple mechanisms in the endocannabinoid…
Bakuchiol is an all-natural alternative to retinol for anyone looking for ways to smooth fine lines, improve glow and brighten skin without using harsh chemicals. Plus, this plant-derived ingredient soothes irritation and sensitivity!Bakuchiol can be used alone or combined with other ingredients like hyaluronic acid, vitamin C and niacinamide to provide effective results. Retinoids or vitamin A formulas should not be mixed as this could cause irritation.1. Bakuchiol SerumBakuchiol increases your skin’s ability to absorb and retain moisture, as well as stimulating cell turnover and providing pigmentation relief. Be sure to add this ingredient into a serum or moisturizer designed…
New research at CU Boulder suggests that CBD may provide better relief than THC-heavy cannabis in terms of anxiety alleviation. CBD works by modulating our bodies’ natural endocannabinoid system – which regulates stress responses and fosters feelings of calm.Studies conducted in clinical settings demonstrate the anxiolytic and anticompulsive actions of CBD, including its ability to decrease autonomic arousal levels, reduce fear expression levels, enhance fear extinction processes, reconsolidation blockade effectiveness, as well as its capacity for mitigating long-term stress effects that contribute to anxiety.How Does CBD Work?CBD interacts with over 65 brain receptors, altering levels of multiple chemicals. Some, like…
Nutrition plays an integral role in maintaining strong bones and healthy muscles from head to toe, as well as supporting an effective immune system and decreasing risk for certain diseases.The classical concept of adequate nutrition is gradually giving way to the new paradigm of optimal nutrition, where the aim is to optimize daily diet in terms of nutrients, non-nutrient properties and functional foods (FFs). The aim is to maintain good health.Strengthens Bones & MusclesIdeal nutrition is at the foundation of healthy lifestyle habits that can reduce osteoporosis-related falls and fractures. Diet plays an integral part in supporting muscular health; specifically…
Detoxifying masks are an excellent way to help combat breakouts, unclog pores, and give skin an overall fresh glow. Detoxifying masks work by creating a negative electric charge that attracts and binds positively charged toxins that have collected within skin cells (1).Start off each week by cleansing and toning your face before applying a detox mask once or twice weekly, followed by toner and serum applications and finishing up with non comedogenic moisturizer like our H2 Oh Yeah!.BlackheadsBlackheads form when pores become clogged with oil and dead skin cells that become trapped within, then turn black due to oxidization. Though…
Migraines can be debilitating, but there are effective ways to prevent and treat them. One approach is recognizing potential triggers – for instance food additives like nitrates and MSG as well as light, sound, glare, odors and stress can all trigger migraine attacks.Experts still do not fully understand what causes migraines, though genetics likely play a part. Preventive medication can help lower your frequency of attacks while rescue medications may shorten or lessen an attack as needed.Get plenty of sleep.Migraine triggers vary significantly among individuals; therefore, your doctor must be aware of your own triggers in order to develop an…
Personal hygiene involves the daily care and upkeep of one’s body to prevent sickness and help people feel clean and confident in themselves.Brushing your teeth, washing your hands and changing your underwear regularly are all great ways to stay germ-free and prevent infections in your body. Other practices for good menstrual hygiene may include using soap that does not irritate intimate areas and visiting your healthcare provider for annual wellness exams (which typically includes pap smear tests). It is vitally important that people observe good menstrual hygiene.Wash Your HandsRegular handwashing is one of the best ways to protect against germs…
If a migraine strikes, its pain, light and sound sensitivity and nausea can be debilitating. But treatments exist that could provide some relief.Migraine medications range from over-the-counter pain relievers such as nonsteroidal anti-inflammatory drugs or acetaminophen (Tylenol) to prescription triptans that prevent migraine headaches from occurring altogether by blocking pain pathways within the brain.Over-the-Counter (OTC) Pain RelieversAs many individuals suffering from episodic migraine use over-the-counter (OTC) medications to soothe their symptoms, taking too many pills could result in medication overuse headaches.At the first sign of migraine symptoms, taking an over-the-counter pain reliever like aspirin, acetaminophen or caffeine can help alleviate…