CBD interacts with complex receptor pathways by antagonizing or activating certain receptors or channels, which then has multiple downstream effects.
CBD may increase blood-thinning medications in your system by competing with liver enzymes that break them down; additionally, it may enhance certain antidepressant and painkiller medicines’ efficacy.
Can CBD Help with Arthritis?
reports and testimonials from people living with arthritis allege that CBD can significantly relieve their symptoms; however, further investigation is required.
CBD’s most often reported benefit is relieving pain, which is one of the primary arthritis symptoms. Other benefits may include improved physical function and better rest; over half of those using it for managing symptoms report using it multiple times per day or more.
Most respondents also use topical CBD products on painful joints. Because these products contain other ingredients like menthol or capsaicin, it’s difficult to pinpoint whether improvements can be attributed to CBD alone.
Does CBD Help with Anxiety?
CBD may be an attractive treatment option for anxiety as it does not interact with the NMDA receptor and has been demonstrated to promote hippocampal neurogenesis in animal models of fear and anxiety. Unfortunately, however, scientific evidence substantiating CBD’s efficacy against anxiety disorders remains limited.
Preclinical studies indicate that systemic CBD may be effective at decreasing anxiety in tests like the elevated plus maze (EPM) and Vogel conflict test (VCT), although its effect on anxiety-related behaviors remains complex. For instance, when administered into the BNST of EPM participants during injection it produced anxiety while being anxiolytic when given post restraint stress in prelimbic cortex after administration into prelimbic cortex via restraint stress; this anxiolytic effect could possibly be mediated through 5-HT1AR and GABAA receptors.
Can CBD Help with Depression?
Many respondents reported using CBD to treat depression. Psychiatrists are concerned that people may not be forthcoming with their doctors regarding any use of unproven psychoactive substances for self-treatment of anxiety and depression, making it harder for physicians to provide patients with appropriate care. Furthermore, CBD may interact with prescription medicines like blood thinners and antiepileptics; additionally it could interfere with liver enzymes responsible for breaking down nonprescription painkillers like Tylenol.
Animal studies suggest that CBD could potentially help with depression by stimulating the brain’s endocannabinoid system and possibly increasing serotonin levels; however, more research needs to be conducted before we can be certain of how effectively it works.
Can CBD Help with Sleep?
Poor sleep has been linked to many health conditions, including depression and anxiety. CBD may assist insomnia by relaxing both the body and mind – making it easier to fall asleep quickly and remain asleep through the night.
CBD may interact with the endocannabinoid system (ECS) and help stimulate serotonin release for improved sleep, thus helping reduce awakenings during the night.
When purchasing CBD for sleep, it is crucial that it meets FDA’s good manufacturing practices for pharmaceutical and dietary supplement products. Look for companies who use a third party lab to conduct quality assurance on each batch to ensure the highest level of product.
Can CBD Help with Pain?
CBD may help relieve pain associated with conditions like fibromyalgia, chronic neuropathy and cancer; however, more research needs to be conducted in order to verify these findings.
Pharmaceutical-grade CBD comes in various forms – capsules designed to be taken orally; tinctures and sprays meant for sublingual administration; oils, creams and patches that can be applied topically; as well as vaping devices capable of directly infusing CBD into bloodstream via lung tissue.
Studies demonstrate the efficacy of CBD oil for relieving symptoms associated with chronic pain, including nausea, neuropathic pain associated with multiple sclerosis or HIV/AIDS, chemotherapy-related pain or any pain in which chemotherapy medications cannot provide relief. It should not be used as an alternative pain management strategy.
Can CBD Help with Addiction?
CBD’s potential to assist with addiction stems from preclinical and clinical reports on its ability to modulate the reinforcing, motivational, withdrawal-related effects of alcohol, opioids (morphine, heroin), psychostimulants (cocaine, amphetamine) and nicotine use. It may do this by modulating dopaminergic, opioidergic, endocannabinoid and glutamatergic systems as well as hippocampal neurogenesis processes.
CBD has also been proven to ease withdrawal symptoms and ease anxiety, restlessness and irritability that accompany addiction recovery. More research needs to be conducted on its efficacy and safety; using it in recovery requires taking an holistic approach with careful thought given to intent, as well as dosing accurately via spray or tincture under the tongue to ensure accurate dosing.
