CBD is generally well tolerated and nonaddictive; the correct dose varies based on a number of factors. Start off slowly before gradually increasing it until reaching your desired effect.
The type of product you choose also plays an integral part in how much CBD you absorb; for instance, gummies and tinctures must first pass through your digestive tract before being fully absorbed.
Dosage
As the CBD industry expands, clearer guidelines on what amounts are safe to consume are necessary. Consumers should start with low doses and observe their body’s response in order to find their optimum dose.
Dependent upon the symptoms you are treating, CBD dosage needs may also depend on this factor. For instance, insomniacs may find a higher dose than someone looking to reduce anxiety.
Other considerations include your body weight and chemistry, as well as the concentration of CBD in the product you’re using. Some packaging for CBD gummies or capsules will indicate how many milligrams of CBD there is per serving; this information can help when determining your ideal dose, particularly when taking multiple supplements simultaneously. Keeping daily intake below certain thresholds will protect liver and reproductive organs from being damaged.
Side effects
CBD usually causes mild side effects that tend to subside when use is stopped or dose reduced, including changes in alertness most commonly experienced as somnolence (sleepiness), gastrointestinal distress such as diarrhea or decreased appetite, and mood changes including irritability and agitation.
Laboratory animals exposed to CBD have shown reduced testicular size and reduced sperm production; more research needs to be conducted in humans before drawing conclusions about this possible effect of taking CBD, however men should exercise caution when taking CBD products and discuss any potential issues with their healthcare provider before beginning therapy with CBD.
CBD may interact with certain medications, including antidepressants such as Paxil (paroxetine), Celexa (citalopram), and Remeron (mirtazapine) as well as benzodiazepine sedatives like Klonopin (clonazepam) and Ativan (lorazepam). This could increase their effects or produce unwanted side effects like drowsiness. Furthermore, CBD could interact with immune-suppressants like Cyclosporine Sandimmune and Tacrolimus (tacrolimum), as well as Rifampin (rifampicin). These interactions could cause increased fatigue as well as side effects from these drugs that could potentially increase their effects or cause unwanted side effects like increased drowsiness, fatigue or other side effects of treatment.
Interactions
CBD interacts with various other drugs broken down by liver enzyme CYP450 and may increase the levels of these substances within the body, leading to greater risks of side effects and toxicity – especially with regards to benzodiazepines, antidepressants, antipsychotics and some herbal supplements.
Combining CBD with other drugs may increase sedation and sleepiness, leading to accidents or falls when driving. CBD can also increase the sedative effects of opioids, SSRIs and tricyclic antidepressants as well as alcohol or other depressants, potentially increasing their sedative properties and leading to accidents or falls when trying to drive.
Studies demonstrate CBD’s anti-anxiety effects in humans. Furthermore, animal models show decreased seizures while its use attenuated GABA release from ventral pallidum neurons in psychotic patients. Furthermore, clinical trials conducted to date show its efficacy at alleviating PTSD symptoms; further research must be completed however.
Precautions
CBD may interact and interact adversely with certain prescription medications, including blood thinners. Because these interactions could potentially be dangerous for some users, it’s wise to discuss your plans for using CBD with both your doctor and pharmacist before proceeding – they can help determine whether this substance is right for you, and give guidance regarding proper dosing.
Dosage of CBD products varies considerably and the optimal strategy is usually to start slowly and increase gradually over time. Many people will find their ideal dosage range between 10-40mg daily. When choosing products like gummies, tinctures, lotions or patches it’s also important to take note of what form it comes in; different chemical components have different ways of being absorbed; quality CBD products with clear labels will ensure optimal absorption rates.
The updated guidelines for daily CBD consumption will prove beneficial to both consumers and producers, providing guidelines that promote health and safety while helping guide future research, regulation, and oversight in the industry.
